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Youzhen Wang Selected Research

S55746

1/2019Combining BH3-mimetics to target both BCL-2 and MCL1 has potent activity in pre-clinical models of acute myeloid leukemia.
4/2018S55746 is a novel orally active BCL-2 selective and potent inhibitor that impairs hematological tumor growth.

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Youzhen Wang Research Topics

Disease

12Neoplasms (Cancer)
11/2020 - 01/2012
3Leukemia
12/2020 - 01/2017
2Hypoxia (Hypoxemia)
11/2020 - 01/2019
2Hepatocellular Carcinoma (Hepatoma)
11/2020 - 01/2019
1Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
12/2020
1Liver Neoplasms (Liver Cancer)
12/2019
1Neoplasm Metastasis (Metastasis)
01/2019
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2019
1B-Cell Lymphoma (Lymphoma, B Cell)
04/2018
1Mantle-Cell Lymphoma (Lymphoma, Mantle Cell)
04/2018
1B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
04/2018
1Lymphoma (Lymphomas)
01/2017
1BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
01/2017
1Gastrointestinal Stromal Tumors (Gastrointestinal Stromal Tumor)
04/2015
1Breast Neoplasms (Breast Cancer)
01/2015
1Pancreatic Neoplasms (Pancreatic Cancer)
02/2014
1Carcinogenesis
10/2013
1Multiple Myeloma
10/2013

Drug/Important Bio-Agent (IBA)

5Pharmaceutical PreparationsIBA
11/2020 - 01/2012
2venetoclaxIBA
12/2020 - 04/2018
2S63845IBA
12/2020 - 01/2019
2Biomarkers (Surrogate Marker)IBA
11/2020 - 01/2019
2roblitinibIBA
11/2020 - 12/2019
2Vinorelbine (Navelbine)FDA LinkGeneric
11/2020 - 01/2019
2S55746IBA
01/2019 - 04/2018
2AlpelisibIBA
01/2015 - 05/2014
1Proteins (Proteins, Gene)FDA Link
12/2020
1Sorafenib (BAY 43-9006)FDA Link
11/2020
1Fibroblast Growth Factors (Fibroblast Growth Factor)IBA
11/2020
1infigratinibIBA
01/2019
1Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA
01/2019
1LigandsIBA
01/2019
1capmatinibIBA
01/2019
1Fibroblast Growth Factor Receptors (Fibroblast Growth Factor Receptor)IBA
01/2019
1Apoptosis Regulatory ProteinsIBA
04/2018
1Tyrosine Kinase InhibitorsIBA
01/2017
1EED226IBA
01/2017
1Polycomb Repressive Complex 2IBA
01/2017
1Imatinib Mesylate (Gleevec)FDA Link
04/2015
1Protein Isoforms (Isoforms)IBA
01/2015
1Phenobarbital (Luminal)FDA Link
01/2015
1Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
01/2015
1Phosphatidylinositols (Phosphatidylinositol)IBA
05/2014
1GemcitabineFDA Link
02/2014
1MEDI-5304IBA
02/2014
1MethyltransferasesIBA
10/2013
1Histone-Lysine N-MethyltransferaseIBA
10/2013
1Monoclonal AntibodiesIBA
01/2012

Therapy/Procedure

3Therapeutics
11/2020 - 05/2014
2Drug Therapy (Chemotherapy)
01/2019 - 01/2019